Thyroid Compounding

Providing compounded thyroid hormone formulations customized to individual patient needs.

Thyroid health plays a crucial role in overall wellness, affecting metabolism, energy levels, and many body functions. When commercial thyroid medications are unable to meet a patient's specific needs, compounding creates personalized, flexible formulations.

How Do Thyroid Hormones Work?

The thyroid gland produces hormones essential for regulating metabolism, energy, and numerous body processes. The two primary thyroid hormones are:

  • T4 (Levothyroxine/Thyroxine): The primary hormone produced by the thyroid, which converts into T3 and regulates metabolism
  • T3 (Liothyronine/Triiodothyronine): The more biologically active thyroid hormone, with a role in regulating energy use and metabolism

Why Thyroid Conditions May Require Compounding

Individualized Dosing

Commercial medications come in fixed strengths. Compounding allows pharmacists to provide micro-doses, intermediate strengths, etc., meeting individual patient needs.

Combination Therapy

Combination T4/T3 therapy allows precise ratios in a single preparation. Some prescribers choose a T4/T3 combination in a specific ratio.

Slow-Release Formulations

Sustained-release T3 is prescribed where a prescriber wants a more gradual release than an immediate-release capsule gives.

Allergen-Free Options

Eliminate common commercial allergens, fillers, and dyes, such as lactose, gluten, cornstarch, soy, artificial dyes, etc., for sensitive patients.

Alternative Dosage Forms

Customize medication into immediate-release capsules, sustained-release capsules, sublingual troches, oral liquids, etc.

Formulations Available

Liothyronine (T3)

  • Immediate-release
  • Sustained-release
  • Custom dosing
  • Allergen-free formulations

Levothyroxine (T4)

  • Custom-release
  • Allergen-free formulations
  • Precise dosing
  • Alternative dosage forms

Combination T3/T4

  • Custom ratios
  • Single capsule for convenience
  • Sustained-release
  • Allergen-free formulations

Related Compounding Services

Thyroid medication is one of the two hormone medications we compound to patient-specific needs. The other hormone medication is bioidentical hormone therapy (BHRT), prepared as creams, troches, capsules, etc., fit to prescriber specifications. Both medications require a prescription. To learn more, our full list is located on compounding services.

Thyroid prescriptions are compounded at our Lake Mary pharmacy for patients in Central Florida, and we also ship across all of Florida. To learn more about the communities we serve, read areas we serve from Lake Mary.

Frequently Asked Questions

Local prescription delivery is free.

Yes, all thyroid medications require a valid prescription from a licensed healthcare provider. Thyroid hormone replacement requires medical evaluation, laboratory monitoring, and ongoing supervision.

T4 (levothyroxine) is the primary hormone produced by the thyroid gland. T3 (liothyronine) is the more active form. Your body converts T4 to T3. Some patients and their providers prefer combination therapy with both hormones.

Thyroid hormones work gradually. It may take several weeks to notice changes, and your provider may need to adjust your dose based on lab results and symptoms. Full optimization may take several months.

Most thyroid medications are best absorbed on an empty stomach, typically 30-60 minutes before eating. However, follow your healthcare provider's specific instructions for your formulation.

Usually for one of three reasons: you need a strength no manufacturer makes, you react to a dye or filler in the commercial tablet, or your prescriber wants a T3 and T4 combination in a ratio that is not sold ready-made. Compounding lets the prescription be written to what you need rather than to what is stocked.

Desiccated thyroid is a manufactured product derived from porcine thyroid glands, containing T4 and T3 in the ratio that occurs in the animal. A compounded T3/T4 preparation is made individually from pharmaceutical-grade thyroid hormones in whatever ratio your prescriber specifies. Which is appropriate for you is a clinical decision; we prepare what is written.

Speak to your prescriber first. Any substitution is their decision and needs a new prescription. Where they choose a compounded route, we can often prepare a T4 and T3 combination to the strengths and ratio they specify. Call (407) 610-9090 with the product and dose you are on now and we will tell your prescriber what is possible.

Your prescriber decides what the equivalent should be; a pharmacy cannot convert a thyroid dose on its own. Once they have written the strengths and the ratio they want, we prepare exactly to that specification. Send or bring your current label so there is no ambiguity about what you have been taking.

It is liothyronine prepared in a base designed to release over a longer period rather than all at once. There is no commercially manufactured sustained-release T3 product, which is why prescribers who want one send the prescription to a compounding pharmacy. Whether it is appropriate for you, and at what strength, is your prescriber's decision.

Usually, yes, and it is one of the most common reasons thyroid prescriptions reach us. Tell us what has to be excluded (dyes, gluten, lactose, corn, a specific filler) when the prescription is sent and we select ingredients accordingly. Put the request in up front rather than after the preparation has been made.

Ask your prescriber to write for a compounded preparation specifying which excipients to avoid. Because we build the capsule from ingredients rather than dispensing a manufactured tablet, we can leave out the filler you react to and use an alternative. Tell us exactly which ingredient caused the problem if you know it.

Because they dispense manufactured tablets, and manufacturers make a fixed set of strengths. If your prescriber has written for something between the standard strengths, below the smallest, or as a combination, there is no product on the shelf to hand over. That prescription needs a compounding pharmacy, which is what we are.

Yes, with a prescription written for it. Custom strengths are the ordinary case in compounding rather than an exception, and small increments matter in thyroid dosing. Your prescriber writes the exact strength they want and each capsule is prepared to it. Call (407) 610-9090 if you want to check a particular strength first.

We compound to USP standards, from ingredients that arrive with a certificate of analysis we review before use, and each prescription is prepared to the specification your prescriber wrote. Compounded preparations are not FDA-approved and are not produced under a manufacturer's batch-release testing. Your prescriber monitors you with labs, which is how thyroid dosing is verified in practice.

Yes, and local prescription delivery is free. We deliver across Central Florida including Lake Mary, Heathrow, Sanford, Longwood, Altamonte Springs, Winter Park, Maitland, and Orlando. Ask for delivery when you send the prescription and tell us where to send it. Call (407) 610-9090 if you are not sure whether we reach you.

Contact Pharmique Pharmacy

Questions about thyroid compounding?

(407) 610-9090
1210 S International Pkwy, Suite 166
Lake Mary, FL 32746
Mon-Fri: 9:00 AM - 5:00 PM
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Important Information

About Compounded Medications: Compounded thyroid medications are prepared by our licensed pharmacy pursuant to a prescription from a licensed healthcare provider. Compounded medications are NOT FDA-approved.

Medical Monitoring Required: Thyroid hormone replacement requires ongoing medical supervision. Regular laboratory monitoring and follow-up appointments are essential. Never adjust your thyroid medication dose without consulting your healthcare provider.